Indexed IF Journals (Corresponding/last authorships: Signori E)
- Cancelliere R, Di Tinno A, Di Lellis AM, Contini G, Micheli L, Signori E. Cost-effective and disposable label-free voltammetric immunosensor for sensitive detection of interleukin-6. Biosensors and Bioelectronics, October 2022, 213, 114467
- Peri D, Deville M, Poignard C, Signori E, Natalini R. Numerical Optimization of Plasmid DNA Delivery Combined with Hyaluronidase Injection for Electroporation Protocol. Computer Methods and Programs in Biomedicine 2019, Accepted 11 November, Published 2020 Apr;186: 105204.
- Signori E, Cavallo F. The Fourteenth International Conference on Progress in Vaccination Against Cancer (PIVAC-14), September 24-26, 2014, Rome, Italy: rethinking anti-tumor vaccines in a new era of cancer immunotherapy.Cancer Immunol Immunother. 2015, 64(10):1349-1356
- Notarangelo MG, Natalini R., and Signori E. Gene Therapy: The Role of Cytoskeleton in Gene Transfer Studies Based On Biology and Mathematics.Curr Gene Ther., 2014, 14(2):121-127
- Chiarella P, De Santis S, Fazio VM, Signori E. Hyaluronidase contributes to the early inflammatory events induced by electrotransfer on the mouse skeletal muscle. Hum Gene Ther., 2013, 24:406-416 (Front Cover in April 2013 Issue)
- Chiarella P, Fazio VM, Signori E. Electroporation in DNA vaccination protocols against cancer, Curr Drug Metabolism, 2013 Mar 1;14(3):291-299
- Chiarella P, Fazio VM, Signori E. Application Of Electroporation In Dna Vaccination Protocols. Current Gene Therapy, 2010, 10(4):281-287
- Signori E, Iurescia S, Massi E, Fioretti D, Chiarella P, De Robertis M, Rinaldi M, Tonon G, Fazio VM. DNA vaccination strategies for anti-tumour effective gene therapy protocols. Cancer Immunol Immunother. 2010, 59(10):1583-1591
- Chiarella P, Massi E, De Robertis M, Fazio VM, Signori E. Recent advances in epitope design for immunotherapy of cancer. Recent Patents Anti-Cancer Drug Discovery, 2009, Nov;4(3):227-240
- Chiarella P, Massi E, De Robertis M, Sibilio A, Parrella P, Fazio VM, Signori E. Electroporation of skeletal muscle induces danger signal release and antigen-presenting cell recruitment independently of DNA vaccine administration. Op. Biol. Ther.2008, 8 (11): 1645-57
- Chiarella P, Massi E, De Robertis M, Fazio VM, Signori E. Strategies for effective naked-DNA vaccination against infectious diseases. Recent Patents Anti-Infective Drug Discovery.2008, 3(2): 93-101
- Chiarella P, Massi E, De Robertis M, Signori E, Fazio VM. Adjuvants in vaccines and for immunisation: current trends. Exp. Op. Biol. Ther. 2007, 7(10): 1551-1562
- Signori E, Rinaldi M, Fioretti D, Iurescia S, Seripa D, Perrone G, Norata GD, Catapano AL, Fazio VM. Intramuscular gene transfer inhibits severe hypercholesterolemia in newborn Apolipoprotein E-deficient mice. Biophys. Res. Commun. 2007, 361(2):543-548
- Signori E, Massi E, Matera MG, Poscente M, Gravina C, Falcone G, Rosa MA, Rinaldi M, Wuyts W, Seripa D, Dallapiccola B, Fazio VM. A combined analytical approach reveals novel ext1/2 gene mutations in a large cohort of italian multiple osteochondromas patients. Genes, Chromosomes and Cancer 2007, 46(5):470-477
Indexed IF Journals (Author Contribution)
- Rocco Cancelliere, Alessio Di Tinno, Andrea Maria Di Lellis, Yannick Tedeschi, Stefano Bellucci, Katya Carbone, *Emanuela Signori*, Giorgio Contini, Laura Micheli.An inverse-designed electrochemical platform for analytical applications. /Electrochemistry Communications/ 2020, 121,106862.
- . 2020 Sep 17;8(3):E537.
- De Robertis Mariangela, Tommaso Mazza, Caterina Fusilli, Luisa Loiacono, Maria Luana Poeta, Massimo Sanchez, Emanuela Massi, Giuseppe Lamorte, Maria Grazia Diodoro, Edoardo Pescarmona, Emanuela Signori, Graziano Pesole, Angelo Luigi Vescovi, Jesus Garcia-Foncillas and Vito Michele Fazio. EphB2 stem-related and EphA2 progression-related miRNA-based networks in progressive stages of CRC evolution: clinical significance and potential miRNA drivers. Molecular Cancer 2018, 17:169
- Marino, N. Olaiz, E. Signori, F. Maglietti, C. Suarez, S. Michinski, G. Marshall. pH fronts and tissue natural buffer interaction in gene electrotransfer protocols. Electrochimica Acta, 2017, Nov 20; 255:463-471.
- De Robertis M., Loiacono L., Fusilli C Poeta ML, Mazza T, Sanchez M, Marchionni L, Signori E, Lamorte G, Vescovi AL, Garcia-Foncillas J, Fazio VM. Dysregulation of EGFR pathway in EphA2 cell subpopulation significantly associates with poor prognosis in colorectal cancer. Clin Cancer Res., 2017 Jan 1;23(1):159-170. Epub 2016 Jul 11
- Sersa G, Teissie J, Cemazar M, Signori E, Kamensek U, Marshall G, Miklavcic D Electrochemotherapy of tumors as in situ vaccination boosted by immunogene electrotransfer. Cancer Immunol Immunother.2015, 64(10): 1315-1327
- Block KI, Gyllenhaal C, Lowe L, …, Signori E, et al. Designing a broad-spectrum integrative approach for cancer prevention and treatment Semin Cancer Biol. 2015 Dec; 35S:S276-S304. doi:10.1016/j.semcancer.2015.09.007.
- Vinay DS, Ryan EP, Pawelec G, Talib WH, Stagg J, Elkord E, Lichtor T, Decker WK, Whelan RL, Kumara HM,Signori E, et al. Immune evasion in cancer: Mechanistic basis and therapeutic strategies. Semin Cancer Biol. 2015 Mar 25. pii: S1044-579 [Epub ahead of print]
- Olaiz*, E. Signori*, F. Maglietti, A. Soba, C. Suarez, P. Turjanski, S. Michinski, G. Marshall. Tissue damage modeling in gene electrotransfer: The role of pH. Bioelectrochemistry2014, 100:105-111. *Equal Contribution
- Lucá R, Averna M, Zalfa F, Vecchi M, Bianchi F, Fata GL, Del Nonno F, Nardacci R, Bianchi M, Nuciforo P, Munck S, Parrella P, Moura R, Signori E, et al. The Fragile X Protein binds mRNAs involved in cancer progression and modulates metastasis formation. EMBO Mol Med. 2013 Oct;5(10):1523-1536
- P Chiarella, V Summa, S De Santis, E Signori, et al. Bcr/Abl1 fusion transcripts generated from alternative splicing: implications for future targeted therapies in Ph+Current Molecular Medicine, 2012 Jun 1;12(5):547-65
- Bordignon V, Cordiali-Fei P, Rinaldi M, Signori E, et al. Evaluation of antigen specific recognition and cell mediated cytotoxicity by a modified lysispot assay in a rat colon carcinoma model. J Exp Clin Cancer Res.2012 Feb 1;31(1):9
- De Robertis M, Massi E, Poeta ML, Carotti S, Morini S, Cecchetelli L, Signori E, Fazio VM. The AOM/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies. J Carcinog.2011 Mar 24;10:9
- Nicolò C, Sali M, Di Sante G, Geloso MC, Signori E, et al. Mycobacterium smegmatis expressing a chimeric protein MPT64-PLP139-151 reorganizes the PLP-specific T cell repertoire favouring a CD8-mediated response and induces a relapsing EAE. Immunol, 2010, Jan 1;184(1):222-35
- Cervelli M, Fratini E, Amendola R, Bianchi M, Signori E, et al.Increased spermine oxidase (SMO) activity as a novel differentiation marker of myogenic C2C12 cells. J. Biochem. Cell. Biol. 2009, 41(4):934-944
- Volpe G, Cignetti A, Panuzzo C, Kuka M, Vitaggio K, Brancaccio L, Perrone G, Rinaldi M, Prato G, Fava M, Geuna M, Pautasso M, Casnici C, Signori E, et al. Alternative BCR/ABL splice variants in Philadelphia chromosome positive leukemias result in novel tumor specific fusion proteins that may represent potential targets for immunotherapy approaches. Cancer Research2007, 67(11): 5300-5307
- Rinaldi M, Signori E, et al. Feasibilty of in utero DNA vaccination following naked gene transfer into pig fetal muscle: transgene expression, immunity and safety. Vaccine2006, 24(21):4586-91
- Signori E, et al. A mutation in the 5’ UTR of BRCA1 gene, causes a down modulation of translation efficiency in a sporadic breast cancer. Oncogene,2001, 20(33):4596-4600
- McMahon JM, *Signori E, et al Optimisation of electrotransfer of plasmid into skeletal muscle by pretreatment with hyaluronidase – increased expression with reduced muscle damage. Gene Therapy, 2001, 8(16): 1264-1270,*Equal contribution
- Rinaldi M, Ria F, Parrella P, Signori E, et al. Antibodies elicited by naked DNA vaccination against hypevariable VH-CDR3 idiotypic determinants of B-lymphoproliferative disorders specifically react with patient's tumor cells. Cancer Research, 2001, 61: 1555-1562
- Rinaldi M,Barrera G, Spinsanti P, Pizzimenti S, Ciafrè SA, Parrella P, Farace MG, Signori E, et al. Growth inhibition and differentiation induction in murine erythroleukemia cells by 4-hydroxynonenal. Free Radical Res. 2001, 34(6): 629-637
- Rinaldi M, Ria F, Parrella P, Signori E, et al. Antibodies elicited by naked DNA vaccination against hypevariable VH-CDR3 idiotypic determinants of B-lymphoproliferative disorders specifically react with patient's tumor cells. Cancer Research, 2001, 61: 1555-1562
- Rinaldi M, Catapano AL, Parrella P, Ciafre SA, Signori E, Seripa D, Uboldi P, Antonini R, Ricci G, Farace MG, Fazio VM. Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by intramuscular injection of plasmid DNA. Gene Ther., 2000, 7: 1795-801.
- Papa S, Rinaldi M, Mangia A, Parrella P, Signori E, Lombardi L and Fazio VM. Development of a multigenic plasmid vector for HCV DNA-immunization. Virol., 1998, 149: 315-319.
- Rinaldi M, Ciafrè SA, Parrella P, Signori E,Farace MG. Saglio G, and Fazio VM Strategies to elicit anti-idiotypic immune response in B-lymphoma patients: peptide and genetic immunizzation. Exp. Med. Biol., 1998, 451: 323-330.
- Ciafrè SA, Rinaldi M, Vespignani I, Parrella P, Seripa D, Signori E, Ria F, Farace MG and Fazio VM. A plasmid family containing two different expression cassettes suitable for immuno-modulation and genetic immunization. Plasmid, 1998, 40(1): 84-89.
Book Chapters (Corresponding authorships: Signori E)
- Mariangela De Robertis, Ursa Lampreht Tratar, Maja Cemazar, and Emanuela Signori.(2016). Predictable animal models for translational electroporation-based cancer immunotherapy studies. In: Handbook of Electroporation: Preclinical Development for Biomedical Application of Electroporation. Damijan Miklavcic (Ed). Springer International Publishing, Switzerland. eISBN: 978-3-319-26779-1
- Chiarella P, and Signori E. Intramuscular DNA vaccination protocols mediated by electric fields. Electroporation Protocols. Preclinical and Clinical Gene Medicine. Methods Mol Biol. 2014, 1121:315-24. Humana Press. Springer Ed., New York (USA). ISBN: 978-1-4614-9631-1; eISBN:978-1-4614-9632-8
- De Robertis M., Fazio VM and Signori E. Murine Models of Sporadic and Inflammation-Related Colon Carcinogenesis with Particular Focus on the AOM/DSS Chemically Induced Colorectal Cancer Model, Animal Modelsnovapublisher in Cancer Research and Human Disease: Applications, Outcomes and Controversies. 2012, Sean A. Murray (Ed), Chapter 1:1-45. Nova Science Publishers, Inc. USA. ISBN: 978-1-62417-587-9
- Chiarella P., Fazio VM. and Signori E. DNA Vaccination by Electrogene Transfer. Non-Viral Gene Therapy. 2011, Xu-bo Yuan (Ed.), Chapter 8:169-198, InTech. ISBN: 978-953-307-538-9
- Chiarella P, Massi E., De Robertis,M., Fazio VM. and Signori E. Strategies for effective naked-DNA vaccination against infectious diseases. "Frontiers in Anti-Infective Drug Discovery". 2010, Vol 1: 1-16, Bentham Science Publishers. ISBN: 978-1-60805-583-8; eISBN: 978-1-60805-158-8
- Rinaldi M, Iurescia S, Fioretti D, Massi E and Signori E. An overview of apoe for application in gene therapy. “Apoprotein Research”. 2009, Chapter 7: 631-634, Nova Science Publishers, Inc. USA. ISBN: 978-1-60692-632-1